EMDocs

JANUARY 6, 2025

Severe malaria management. 84 Adapted from: World Health Organization (WHO). WHO Guidelines for Malaria.; Accessed June 11, 2023. Lassa fever: epidemiology, clinical features, and social consequences. 2003;327(7426):1271-1275. doi:10.1136/bmj.327.7426.1271 327.7426.1271 World Health Organization (WHO). Lassa Fever.; Accessed October 23, 2024.

ED 73

ED E-9-1-1 ALS Frozen Plasma 73

EMDocs

MAY 17, 2025

9 Current best practice suggests a 1:1:1 administration of PRBC, Platelets, and FFP. Balanced transfusion of packed red blood cells (PRBCs), platelets and fresh frozen plasma (FFP) in a 1:1:1 ratio is the current best practice to avoid inducing coagulopathy by large volume blood product administration.

E-9-1-1 102

E-9-1-1 EMS FFP Frozen Plasma 102

EMDocs

MAY 27, 2025

11 Transfuse patients who are anemic or coagulopathic, ideally with fresh whole blood; if this is not available, use packed red blood cells (PRBCs) for anemia, and replete coagulopathy with platelets, fresh frozen plasma (FFP), or cryoprecipitate as indicated. 2017;55(7):2009-2017. Clinical Testing and Diagnosis for Malaria.;

ED 81

ED Plasma Frozen Plasma ALS 81

Core EM

JANUARY 24, 2024

2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. Background Around 6 million people in the U.S. Background Around 6 million people in the U.S. Background Around 6 million people in the U.S.

FFP 130

FFP Frozen Plasma Plasma ALS 130

REBEL EM

SEPTEMBER 13, 2023

J Allergy Clin Immune Tract 2017; 5(5): 1402-9. PMID 20954277 Sinnert R et al. Randomized Trial of Icatibant for Angiotensin- Converting Enzyme InhibitoreInduced Upper Airway Angioedema (CAMEO Study). PMID: 28552382 Wilkerson RG. Angioedema in the Emergency Department: An Evidence Based Review. Emergency Medicine Practice. EBMedicine.net.

Frozen Plasma 99

Frozen Plasma Allergic Reaction FFP Plasma 99

Core EM

JANUARY 25, 2024

Annual incidence of approximately 2-4 cases/million/year (Kappler, 2017), with 90% of cases occurring in adulthood. Joly, 2017) Risk factors include: Female, 2:1 female to male predominance (Terrell, 2010) Black race Obesity TTP is a life-threatening condition with mortality of 10-20% despite targeted therapies.

Plasma 247

Plasma Frozen Plasma Emergency Department FFP 247

REBEL EM

JUNE 26, 2023

Lancet Haematol 2017. Severe acute traumatic coagulopathy = PT >1.5 to 3.33; P = 0.72 NOT STATISTICALLY SIGNIFICANT Also no difference in individual components given Thromboembolic Events: 4F-PCC: 35% Placebo: 24% Absolute Diff: 11%; 95% CI 1 to 21% Relative Risk 1.48; 95% CI 1.04 to 2.10; P = 0.03 PMID: 28457980 Jehan F et al.

FFP 140

FFP Frozen Plasma ALS Plasma 140