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ED care of refugee populations from sub-Saharan Africa

EMDocs

Severe malaria management. 84 Adapted from: World Health Organization (WHO). WHO Guidelines for Malaria.; Accessed June 11, 2023. Lassa fever: epidemiology, clinical features, and social consequences. 2003;327(7426):1271-1275. doi:10.1136/bmj.327.7426.1271 327.7426.1271 World Health Organization (WHO). Lassa Fever.; Accessed October 23, 2024.

ED 74
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EM@3AM: Systematic Approach to Massive Hemorrhage and Nuances in Special Patient Populations

EMDocs

Balanced transfusion of packed red blood cells (PRBCs), platelets and fresh frozen plasma (FFP) in a 1:1:1 ratio is the current best practice to avoid inducing coagulopathy by large volume blood product administration. 17 TEG and ROTEM are non-invasive tests that quantitatively measure the ability of whole blood to form a clot.

E-9-1-1 105
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Severe Malaria: ED Presentation, Evaluation, and Management

EMDocs

11 Transfuse patients who are anemic or coagulopathic, ideally with fresh whole blood; if this is not available, use packed red blood cells (PRBCs) for anemia, and replete coagulopathy with platelets, fresh frozen plasma (FFP), or cryoprecipitate as indicated. 2017;55(7):2009-2017. Clinical Testing and Diagnosis for Malaria.;

ED 83
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SGEM#251: Nothing Compares to You…Because there was No Comparison Group

The Skeptics' Guide to EM

In contrast, protamine could be used for heparin and LMWH reversal and vitamin K, fresh frozen plasma and prothrombinase complex concentrate could be used to reverse coumadin ( Hunt and Levi BMJ 2018 ). This changed in 2015 when the Food and Drug Administration (FDA) approved idarucizumab for the reversal of dabigatran.

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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Fresh frozen plasma for progressive and refractory angiotensin-converting enzyme inhibitor-induced angioedema. J Allergy Clin Immune Tract 2017; 5(5): 1402-9. Read More EMCrit: Podcast 145 – Awake Intubation Lecture from SMACC ERCast: Angioedema References: Baş M et al. N Engl J Med. 2015; 372(5):418-25. EBMedicine.net.

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Anticoagulation Reversal

Core EM

2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. Background Around 6 million people in the U.S. Background Around 6 million people in the U.S.

FFP 130
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Thrombotic Thrombocytopenic Purpura (TTP)

Core EM

Annual incidence of approximately 2-4 cases/million/year (Kappler, 2017), with 90% of cases occurring in adulthood. Joly, 2017) Risk factors include: Female, 2:1 female to male predominance (Terrell, 2010) Black race Obesity TTP is a life-threatening condition with mortality of 10-20% despite targeted therapies.

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