Medetomidine Overdose: Why More Naloxone Is Not the Answer—But Timely Respiratory Support Is
JEMS
JUNE 13, 2025
Importantly, these overdoses are often incompletely responsive to naloxone, creating confusion and concern among first responders. ACS Chemical Neuroscience, 15(21), 3874–3883. In one surveillance program in Philadelphia, medetomidine was found in 72% of fentanyl samples, surpassing even xylazine in prevalence. References 1.
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