Medetomidine Overdose: Why More Naloxone Is Not the Answer—But Timely Respiratory Support Is
JEMS
JUNE 13, 2025
Importantly, these overdoses are often incompletely responsive to naloxone, creating confusion and concern among first responders. Medetomidine acts independently of the opioid receptors and cannot be reversed by naloxone. 2 Withdrawal from medetomidine presents a different challenge. 2,6 What About Withdrawal?
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