Don't Forget the Bubbles

OCTOBER 28, 2024

Surprisingly, there are different definitions of paediatric major haemorrhage, with no single agreed-upon definition. Many of these definitions are not useful in acutely bleeding children as they require measuring the amount of blood that was lost or transfused over prolonged periods. What is major haemorrhage?

Frozen Plasma

EMDocs

JANUARY 6, 2025

Cholera Case Definitions and Diagnosis.; Severe malaria management. 84 Adapted from: World Health Organization (WHO). WHO Guidelines for Malaria.; Accessed June 11, 2023. 2020;38:A73-A82. doi:10.1016/j.vaccine.2019.07.099 2019.07.099 Centers for Disease Control and Prevention (U.S.). Zinc Treatment. Published online November 14, 2022.

ED

Core EM

AUGUST 1, 2025

Angioedema – Recognition and Management in the ED Hosts: Maria Mulligan-Buckmiller, MD Brian Gilberti, MD [link] Download Leave a Comment Tags: Airway Show Notes Definition & Pathophysiology Angioedema = localized swelling of mucous membranes and subcutaneous tissues due to increased vascular permeability.

Frozen Plasma

EMDocs

MAY 17, 2025

General principles in the approach to massive hemorrhage Definition of Massive Hemorrhage: Definitions of major hemorrhage include: Loss of more than one circulating blood volume within 24h, loss of 50% of total blood volume in <3h, or bleeding in excess of 150mL/min. Also useful in Hemophilia C 1 unit of factor/mL of FFP.

E-9-1-1

EMDocs

MARCH 18, 2025

Episode 116: Massive Hemoptysis Definition: Hemoptysis is expectoration of blood from the respiratory tract; ranges from mild with small streaks of blood to cardiopulmonary compromise (1-5). Massive hemoptysis: no clear definition, ranges from 50 mL in a single expectoration to 100 mL in 24 hours to over 1 L in 48 hours. microg/kg IV.

E-9-1-1

Emergency Medicine Ireland

OCTOBER 28, 2020

There is a definitely a chance to shine and make the diagnosis. Theoretically giving them FFP while waiting on PLEX seems like it might be sensible but in reality probably does nothing when the autoantibodies are still around. This is form of MAHA (microangiopathic haemolytic anaemia).

Critical Care

Don't Forget the Bubbles

JUNE 30, 2023

a) A balanced ratio of 1:1:1 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. b) A balanced ratio of 1: 1:2 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. And blood comes out. Quite quickly. Time to get a transfusion started.

E-9-1-1