Core EM

OCTOBER 2, 2024

Philadelphia, PA: Wolters Kluwer; 2015:979-984. Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

Allergic Reaction 100

Allergic Reaction Plasma ED Epinephrine 100

The Overrun

JUNE 3, 2023

Through the years, we see a change to plasma, then crystalloid, and then 1:1:1 therapy. Once compared, while 1:1:1 therapy or giving PRBCs or plasma alone is better than crystalloid, whole blood is preferable and may have more of a survival benefit for patients. In the First World War, the preferred resuscitation fluid was whole blood.

Plasma 52

Plasma Paramedicine Paramedicine EMS 52

Don't Forget the Bubbles

NOVEMBER 15, 2023

Have a look to see how their osmolarity and tonicity across the cell membrane compare to plasma. Renal (= urine output) : anti-diuretic hormone (ADH) release from the posterior pituitary is stimulated by microchanges in plasma osmolarity. What loss mechanisms do we need to consider? A fluid shift, if you will. Lancet (London, England).

Plasma 78

Plasma ALS ICU Critical Care 78

EMDocs

JULY 13, 2024

Plasma cell endometritis is associated with Chlamydia trachomatis infection. 2015 Feb 2;2015(2):CD001067. Chorioamnionitis and endometritis. Infect Dis Clin North Am. 1997 Mar;11(1):203-22. doi: 10.1016/s0891-5520(05)70349-4. PMID: 9067792. Paukku M, Puolakkainen M, Paavonen T, Paavonen J. Am J Clin Pathol. 1999 Aug;112(2):211-5.

EMS 83

EMS E-9-1-1 Plasma OR 83

Dr. Smith's ECG Blog

FEBRUARY 18, 2022

In fact, there is laboratory evidence that CO toxicity increases Plateletneutrophil aggregates and plasma myeloperoxidase (MPO) concentration and thus may precipitate ACS (though this is by no means clinically proven). Intravascular Neutrophil Activation Due to Carbon Monoxide Poisoning What do you think of this ECG?

ACS 52

ACS Plasma OR STEMI 52

The Skeptics' Guide to EM

DECEMBER 17, 2022

The transfusion tech calls to remind you that your protocol is currently under review, and asks if would you like the 1:1 or the 1:3 version of fresh-frozen plasma (FFP) to packed red blood cells (pRBC)? Noting with some relief that at least he isn’t anticoagulated, you activate the hospital massive transfusion protocol. years ( 2 ).

Frozen Plasma 130

Frozen Plasma FFP Plasma Emergency Medical Services 130

REBEL EM

MAY 25, 2023

JAMA 2015 [7] The PROPPR Trial 680 severely injured adult trauma patients Patients randomized to Plasma, Platelets, and PRBCs in a 1:1:1 ratio vs 1:1:2 ratio No difference in overall mortality at 24 hrs BUT 1:1:1 achieved hemostasis faster and fewer experienced death due to exsanguination at 24hrs Crombie N et al. Ann Emerg Med.

E-9-1-1 145

E-9-1-1 Plasma ALS OR 145

Don't Forget the Bubbles

JUNE 30, 2023

This was a randomised controlled multisite study comparing resuscitation of trauma patients requiring massive transfusion using either 1:1::1 or 1:1:2 ratios of platelets to plasma to red blood cells. Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: design, rationale and implementation. 2015 Jul;115(1):76-83.

E-9-1-1 140

E-9-1-1 FFP Plasma Emergency Department 140

FOAMfrat

AUGUST 15, 2024

Moreover, LTOWB also allows us to administer platelets and plasma, in addition to red cells, to promote clotting and homeostasis. If you don't have access to LTOWB and are administering component therapies such as PRBCs or plasma, this is still incredible and I highly encourage it! Like I said, some blood is better than no blood!

Plasma 69

Plasma ALS Ambulance Emergency Department 69

EMDocs

JUNE 12, 2024

Two randomized controlled trials by Moore et al found that prehospital plasma administration in trauma patients is associated with hypoCa (53% vs 36%). How does this impact the prehospital environment? Prehospital blood product transfusion increases risk of hypoCa. Anaesth Intensive Care. 2011;39(1):46-54. Li K, Xu Y. Int J Clin Exp Med.

FFP 100

FFP ALS Plasma Emergency Department 100

EMDocs

JUNE 3, 2023

Institutional protocols should be utilized, keeping in mind that either whole blood or a 1:1:1 ratio of packed red blood cells, platelets, and fresh frozen plasma are optimal. link] Published June 23, 2015. Young and Burgess classification of pelvic ring fractures. Radiopaedia.org. Published November 8, 2022. Radiopaedia.org.

ED 61

ED Operating Room ALS Frozen Plasma 61

FOAMfrat

SEPTEMBER 19, 2024

Along with inducing coagulopathy, venom toxins may contribute to local and/or systemic hemorrhage and plasma extravasation by means of basement membrane degradation within the vasculature. Other venom toxins carry a fibrinogenolytic effect which hinders coagulation (anticoagulation). Wilderness & Environmental Medicine , vol.

Emergency Department 95

Emergency Department Epinephrine OR Plasma 95

EMDocs

JULY 19, 2023

However, in extreme cases with highly toxic levels, one could consider plasma exchange if no other suitable alternative exists. 2015, March 26). Chelation is generally indicated in cases where patients are experiencing symptoms of toxicity (even the vague, non-specific ones) or there are elevated concentrations of mercury in blood.

ACS 87

ACS Plasma OR ED 87

Don't Forget the Bubbles

JULY 5, 2023

SCD, therefore, is not only a mechanical disease but there are also many other cellular and plasma factors as well as endothelial interaction that generate chronic inflammation. Anemia ; 2015.DOI:10.1155/2015/791498. DOI:10.1155/2015/791498. Plast Reconstr Surg – Glob Open 2015; 3: 83–86. References Adewoyin AS.

E-9-1-1 125

E-9-1-1 ACS OR ICU 125

Core EM

JANUARY 16, 2025

Figure 1: Cumulative success rate at intubation, modified from (Je, 2015) The ACGME-defined minimum of 35 intubations to graduate would suggest a failure rate of 20%, or 1 out of every 5 intubationsthis is obviously not an acceptable percentage for such a consequential procedure. Pre-oxygenate with BiPAP (Farkas 2015).

E-9-1-1 130

E-9-1-1 EMS ALS OR 130

EMDocs

NOVEMBER 2, 2024

The development of an inflammatory process is largely due to the infiltration of lymphocytes and plasma cells which ultimately result in nerve damage (e.g., 2015 Dec;21(6 Neuroinfectious Disease):1714-28 Carlson JA, Dabiri G, Cribier B, Sell S. demyelination as in tabes dorsalis) and subsequent death [10]. Accessed July 19, 2024.

EMS 103

EMS E-9-1-1 Plasma ALS 103