Peter Canning

JUNE 20, 2025

Once a month, the CDC releases their provisional fatal overdose data based on a 12-month rolling average. Lately, each month the release of the data has led to glowing articles about overdoses going down, which they had been for some time — quite substantially. The CDC’s data is 4 months behind. More on that in a moment.

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JEMS

JUNE 16, 2025

15 min read Mobile Integrated Health and Community Paramedicine News News Feed Community Paramedic Headlines News Feed Oregon Medetomidine Overdose: Why More Naloxone Is Not the Answer—But Timely Respiratory Support Is A new nonopioid sedative, medetomidine, is rapidly becoming the next adulterant of concern in illicit drug supply.

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Peter Canning

DECEMBER 6, 2024

Why are overdoses fatalities dropping? Today, I want to examine one possible factor — the increasing presence of xylazine in the drug supply, which I have written about before Xylazine Hysteria Xylazine Decreases Overdose Deaths? All have seen declining fatal overdose rates. Overdose deaths are down significantly.

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JEMS

JUNE 25, 2025

Hyoung Chang/The Denver Post/TNS) Nick Coltrain – The Denver Post DENVER — Colorado will use $3 million from the state’s opioid settlement fund to provide the overdose-reversal drug naloxone to local organizations, Attorney General Phil Weiser announced Tuesday. 1 to April 28, compared to 168 in the same period in 2024.

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JEMS

JUNE 26, 2025

It’s offering naloxone, an emergency medication used to reverse opioid overdoses, for free. Naloxone, also known by the brand name Narcan, reverses opioid overdoses by attaching to opioid receptors in the brain and blocking other opioids. 4, 2018, in Philadelphia. (AP But it’s not selling candy or snacks or soda.

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Peter Canning

JUNE 25, 2025

If they’re lethargic and hard to arouse, but still breathing effectively, it’s not an overdose. Boston paramedic This is a quote I included in a presentation I put together for the state of Connecticut back in 2014 when we designed a curriculum to teach BLS providers how to use naloxone. Fatal overdoses are easy to track.

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Peter Canning

NOVEMBER 9, 2024

This expansion should include patients in prison, many pf whom are in jail due to the substance use disorder and who are at high risk of overdose and death on their release, The US will continue to support harm reduction, including widespread naloxone availability, syringe exchange and the development of overdose prevention sites.

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JEMS

JULY 11, 2025

In a statement Thursday evening, Baltimore Mayor Brandon Scott’s office said the event remained under investigation and that officials had not yet confirmed what caused the overdoses. The Baltimore Police Department] continues to investigate the scene and surrounding neighborhoods, focusing on the source of the overdose event.

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Peter Canning

JULY 7, 2025

We respond for the “overdose.” They thought you were overdosed.” I leave a naloxone kit with them. Was this a drug overdose? Other than the fact that a badly mixed bag of fentanyl can kill you on the spot if no one gives you naloxone after you stop breathing.) His eyes are closed, his mouth is open.

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EMDocs

JULY 2, 2025

5,6 While its effects on cardiac conduction are less pronounced than TCAs, tianeptine still poses risks for arrhythmias, especially in cases of overdose or misuse. Pharmacological Interventions: Naloxone: Because of tianeptine’s µ-opioid receptor agonism, naloxone may partially reverse respiratory depression and sedation.

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JEMS

JUNE 25, 2025

EMS Equipment & Gear News California Headlines More News CO Will Give $3 Million Grant to Boost Naloxone Supply as Data Shows Drop in Overdose Deaths Colorado will use $3 million from the state’s opioid settlement fund to provide the overdose-reversal drug naloxone to local organizations.

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JEMS

JULY 11, 2025

Shelton/Mississippi Today/KFF Health News/TNS) Grace Zokovitch – Boston Herald Opioid related overdose deaths fell 36% in Massachusetts in 2024, reaching their lowest point since 2013, according to provisional CDC data. The naloxone kits contributed to the reversal of at least 7,500 overdoses in 2024, the department stated.

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Peter Canning

MAY 1, 2025

The 119 million or 238 million lives saved in 100 days claim does not give us much confidence in those at the top leading the fight, particularly given reports of a potential administration budget proposal to cut funding for naloxone and other overdose prevention programs. Notes: I n 2024, the DEA seized 60 million fentanyl pills.

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Peter Canning

APRIL 24, 2025

I am proud to announce my latest book, The Friends and Family Guide to the Opioid Overdose Epidemic: Including How to Recognize and Treat an Overdose , will be published on August 26, 2025 by Johns Hopkins University Press. The opioid crisis in the United States continues to kill Americans at an alarming rate.

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EMDocs

JUNE 28, 2025

Reversal of the effects of clonidine using naloxone. Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies. Flumazenil in benzodiazepine overdose. Risk factors for bradypnea in a historical cohort of surgical patients receiving fentanyl-based intravenous analgesia. JA Clin Rep. 2018;4(1):46.

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ACEP Now

JUNE 4, 2025

Drug overdoses are a leading cause of accidental death in the United States, representing a persistent and escalating health crisis. 1 Even in nonfatal opioid overdose cases, there is a significant increase in both short- and long-term mortality. One study found a 5.5 percent occurred within just two days of discharge.

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Peter Canning

JUNE 8, 2025

Increased Availability of Naloxone 2. This week here in Connecticut, we experienced a large spike in overdoses prompting an advisory from the federal High Intensity Drug Trafficking Area (HIDTA) Overdose Response Strategy group. There have been many reasons speculated for the drop in fatal deaths: 1.

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JEMS

JUNE 25, 2025

EMS Equipment & Gear News California Headlines More News CO Will Give $3 Million Grant to Boost Naloxone Supply as Data Shows Drop in Overdose Deaths Colorado will use $3 million from the state’s opioid settlement fund to provide the overdose-reversal drug naloxone to local organizations.

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JEMS

JUNE 25, 2025

2 min read EMS Operations News News Feed Headlines Massachusetts CO Will Give $3 Million Grant to Boost Naloxone Supply as Data Shows Drop in Overdose Deaths Colorado will use $3 million from the state’s opioid settlement fund to provide the overdose-reversal drug naloxone to local organizations.

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The Skeptics' Guide to EM

SEPTEMBER 21, 2024

Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California. Your partner asks if you want to administer naloxone as well. Today’s study looks at the role of naloxone in OHCA. Naloxone is a well-established medication used primarily for reversing opioid overdoses. JAMA Network Open.

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Emergency Medicine Cases

OCTOBER 23, 2018

Aaron Orkin discuss the latest in naloxone in opioid overdose cardiac arrest and altered LOA, a 5-step approach to ED opioid withdrawal management and how we can improve mortality and morbidity in patients with opioid use disorder in the era of the opioid epidemic.

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EMDocs

NOVEMBER 6, 2023

Opioid overdose remains the leading cause of cardiac arrest due to poisoning in North America. Naloxone administration may reverse respiratory arrest, preventing progression to cardiac arrest. Editorial Comment: Naloxone first, flumazenil only for pure benzo’s (e.g., COR No Benefit, LOE C-EO. COR Harm, LOE B-R.

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Emergency Medicine Cases

OCTOBER 9, 2018

In anticipation of EM Cases Episode 116 on Opioid Misuse, Overdose and Withdrawal, Dr. Michelle Klaiman, Addictions and Emergency Medicine specialist, tells her Best Case Ever exemplifying how we can positively impact the lives of ED patients for years to come - even when they present with simple, run-of-the-mill diagnoses - by thinking outside the (..)

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Peter Canning

JANUARY 27, 2024

In the case of naloxone, unlike say milk, the product doesn’t spoil and it retains its potency for many years. Yes, naloxone works for years after its expiration date. One study showed naloxone stayed viable even after thirty years of storage in a less than ideal setting.

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Peter Canning

DECEMBER 6, 2023

I take the naloxone out of my med kit, draw up a small amount in a syringe and slowly push it through the IV. Rest, you overdosed. We had to give you naloxone. We had to give you naloxone. He overdosed?” We gave him a little naloxone and he came around. You should have naloxone in your house.

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Prehospital Emergency Care Podcast

MAY 21, 2021

Melody Glenn ( @MGlennEM ) Dr. Jeremy Cushman ( @hws96 ) about their manuscripts Refusals After Prehospital Administration of Naloxone during the COVID-19 Pandemic and Degree of Bystander-Patient Relationship and Prehospital Care for Opioid Overdose EMS Chain of Survival while discussing the idea of utilizing a Chain of Survival for patients suffering (..)

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Prehospital Emergency Care Podcast

JULY 28, 2022

As always THANK YOU for listening. Hawnwan Philip Moy MD ( @pecpodcast) Scott Goldberg MD, MPH ( @EMS_Boston ) Jeremiah Escajeda MD, MPH ( @jerescajeda ) Joelle Donofrio-Odmann DO ( @PEMems) Maia Dorsett MD PhD ( @maiadorsett ) Lekshmi Kumar MD, MPH ( @gradyMED1 )

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Dr. Smith's ECG Blog

NOVEMBER 1, 2022

He awoke with naloxone. The 50-something patient with history of coronary stenting and slightly reduced LV ejection fraction. He had been smoking an opiate and suddenly collapsed. He was ventilated with BVM on arrival. This EKG was recorded as part of a standing order for critical care. He denied any CP or SOB.

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Peter Canning

JANUARY 14, 2024

Here are some of the highlights: EMRs and EMTs may administer Naloxone IM in a dose of 0.4 Paramedics may administer buprenorphine to patient in precipitated withdrawal following naloxone resuscitation provided the patient meets required criteria and agrees to hospital transport.* mg via syringe.* micrograms/kg/min.

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Dr. Smith's ECG Blog

MAY 5, 2023

Krantz et al authored a State-of-the-Art Review on Cardiovascular Complications of Opioid Use ( JACC 77(2):205-223, 2021 ) — in which mechanisms from Opioid Overdose that detail arrhythmia production ( up to cardiac arrest ) are elucidated — thereby providing an explanation for the unusual arrhythmias in today's case.

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ACEP Now

JULY 7, 2023

Patients with opiate overdose get naloxone. This month, we are discussing the medical management of patients with mild to moderate agitation. Emergency departments (EDs) focus on rapid initiation of medical treatment. Patients with sepsis get antibiotics. Patients in DKA get insulin.

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The Good, The Bad & The Ugly Paramedic

MARCH 1, 2021

An accidental opioid overdose and its nemesis, naloxone. Find It In Advance By paying heed to gut instinct and weighing up the pros and cons, we begin to build a clearer picture in the mind around methods to help us manage, or undo, the unwanted effects of interventions. Some start to sink in right from the early days of education.

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The Skeptics' Guide to EM

MAY 21, 2017

Do heroin overdose patients require observation after receiving naloxone? He is also the host of EMToxCast and gave a talk at the Association of Academic Chairs of Emergency Medicine Annual Retreat […] The post SGEM#179: Chase the Dragon and Naloxone first appeared on The Skeptics Guide to Emergency Medicine.

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ALiEM

NOVEMBER 29, 2023

Recently, xylazine has gained attention in the media with increasing reports of xylazine-related overdose deaths in patients. When combined with illicit opioids such as heroin and fentanyl, xylazine may increase the risk of fatal overdose given the augmented sedation and respiratory depression effects [2]. Published May 2023.

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The Skeptics' Guide to EM

JANUARY 19, 2019

Hospital Observation Upon Reversal (HOUR) With Naloxone: A Prospective Clinical Prediction Rule Validation Study. Hospital Observation Upon Reversal (HOUR) With Naloxone: A Prospective Clinical Prediction Rule Validation Study. The EMS crew observes drug paraphernalia and suspect an intravenous (IV) opioid overdose.

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Peter Canning

SEPTEMBER 10, 2024

Across the nation states are passing initiatives to allow EMS services to leave naloxone kits on scene with at risk patients, their family, friends or bystanders. Each kit contains two 4 mg Naloxone intranasal devices, and instruction card for use, a CPR face shield, and instructions on how to access services.

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The Skeptics' Guide to EM

AUGUST 27, 2022

Case: A 24-year-old male presents to the emergency department (ED) after a fentanyl overdose. He is successfully resuscitated using naloxone and is stable after an observation period. You are interested in seizing this opportunity to offer some type of help to this patient to prevent another opioid overdose in his future.

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